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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are usually characterized by a focus on practical aspects of the study design, including recruitment and consent, 프라그마틱 슬롯버프 adherence, and the use of commonly available equipment.

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A pragmatic trial that uses a variety investigators and includes participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is essential for practical trials to be valid, and it also helps to reduce the chance of bias in the results. However too much heterogeneity could result in problems with the design of the trial.

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The purpose of pragmatic trials is to replicate real-life situations and achieve the highest level of validity externally. Usually, 프라그마틱 홈페이지 they are ordered by policymakers and practitioners to guide their decisions. They are also a good way to identify the cause-effect relationship between an intervention and its outcomes. However, they should not be used to replace explanatory studies.

The idea of pragmatism is controversial and there are concerns about whether pragmatic trials can replace explanatory tests or 프라그마틱 슬롯 무료체험 if they are an addition to them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which confirm a physiological hypothesis or clinical hypothesis, 프라그마틱 슬롯체험 and pragmatic trials that aid in policy and practice decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool tried to define the characteristics of a pragmatic study which includes recruitment, design, delivery of the intervention, and follow-up.

The number of pragmatic trials is increasing. A recent Medline query that used the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to keep in mind that the majority of these studies were conducted in primary care settings.