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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are usually characterized by a focus on the practical aspects of research design, like recruitment and consent in adherence, as well as the use of routinely available equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used various investigators and included participants from various geographical areas. This kind of heterogeneity is necessary for pragmatic trials to be able to prove their validity, and 프라그마틱 홈페이지 it also reduces the chance of bias in the results. However too much heterogeneity could cause issues with the design of the trial.

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The aim of pragmatic trials is to mimic real-life scenarios and gain maximum credibility externally. They are usually requested by practitioners and policy makers to aid in their decision-making. They also provide a useful method of determining the causal relationship between the intervention and its effects. However, they should not be used to substitute for 프라그마틱 슬롯 무료 explanatory studies.

The pragmatism idea is controversial, and there are doubts about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which support the physiological hypothesis or clinical hypothesis, as well as pragmatic trials that aid in the decision-making process for policy and practice. They also proposed an approach to pragmatic trials, dubbed PRECIS.2 This tool attempted to define the features of a practical trial that include the recruitment process, the design and delivery of the intervention, as well as follow-up.

The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and 프라그마틱 순위 pragmatic, limited to controlled trials that are randomized (RCTs), yielded 34 articles, as shown in red in Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to remember that the majority of these studies were conducted in primary-care settings.