The BIOFIRE System and Your Immune System

The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to select the right test first time. Patients benefit from faster diagnosis and more specific treatment. Clinicians benefit from improved stewardship for antibiotics. Labs save money and gain efficiency.

The BioFire FilmArray Pneumonia plus panel (PN panel) tests native sputum, endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens with clinical relevance and antimicrobial resistance genes with semiquantitative results in about an hour.

Respiratory

The burning of biomass (wood plants, agro-forestry and other organic material) creates gaseous pollutants and fine particles that adversely affect the respiratory system. Climate change can make it more difficult to reverse the negative effects of forest fires to the health of humans.

In the United States wildfire smoke is linked to hospitalizations due to respiratory diseases such as asthma, COPD, and lung cancer. This type of pollution can also increase the risk of developing cardiovascular diseases and is a major cause of the burden of disease in the most vulnerable populations.

The wildfires have caused unhealthy levels of air pollutants in several communities during the COVID-19 epidemic. The response of public health has been limited to a communications campaign about symptom management. This lack of knowledge is concerning due to the evidence of possible health hazards from the continued exposure to smoke and other causes of poor air quality.

Researchers are now looking at the best way to safeguard public's health during any future events of this nature. NIH is a research institution that studies this important public health issue through the BLUE CORAL and Bioethanol Fire Bowl CORAL studies.

First time, a prospective study will examine the long-term effects of exposure to smoke from wildfires and other sources. FIRE CORAL is seeking adult participants hospitalized for COVID-19's index episode who have a fluency in English or Spanish and are not pregnant. The protocol for ethanol fire Coral includes a battery in-person assessments that objectively assess pulmonary function testing, lung imaging and functional assessment.

Smoke and other particles can cause or worsen chronic respiratory conditions like emphysema COPD and pneumonia. A number of steps can be taken to stop or minimize the negative health effects of exposure to smoke, such as avoiding outdoor activities when feasible and wearing the EPA's "N95" mask that is designed to capture fine particles.

Smoking can cause irritation to the eyes and throat, and lead to an irritated nose. To minimize symptoms the lungs need to be flushed with plenty of water and taking medicines that decrease inflammation, such as corticosteroids.

Bloodstream

Your bloodstream is on the front lines of fighting off germs that enter your body. Dendritic cells are special cells, act as a call center for your fire department. They collect antigens from bacteria and release proteins to signal other white cells to fight them. The total number of white blood cells, differentials, and band cells increased after firefighters' firefighting tasks as compared to levels following strenuous exercise without fire-fighting.

Skin

As the wildfires in California spewed smoke and smoke into the air during winter and fall dermatologists were concerned how that might affect the skin of those who were exposed to it. Maria Wei, a graduate student at the University of California, Irvine is researching how extreme fire pollution affects skin. Her research was published in Scientific Reports on April 22nd.

The study by Wei shows that temperature changes of the skin dependent on the amount of time the body has been exposed. It can take as long as two hours for the skin of an individual to reach its "flash point"--the point where it begins to burn and then turns into ash. It's important not to stay near a campfire or bio ethanol indoor bio-ethanol fireplace (gatealibi6.werite.net) fire and wear protective clothing if outdoors in a humid or hot day.

Forest fires will continue to occur, despite the measures taken to prevent fires from causing pollution. Wei is forecasting that the number of people suffering from the effects of wildfires will rise as climate change causes more and more forests to burn. This means that more people will need to wear long sleeves and hats and thick moisturizers.

Wildfire air pollution can also exacerbate atopic skin dermatitis, which is a condition that causes itchy skin in many people. She claims that the particles in smoke can clog pores, making atopic skin worse.

Atopic dermatitis may also make people more sensitive to UV light. This is often exacerbated by smoke from wildfires. This can result in people seeking out tanning salons to tannish with less protection.

While a cold and fire facial may help reduce the effects of atopic dermatitis, it is not safe for anyone with an open wound or rash on their face. This treatment is not recommended for people with active acne, or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' premiere membership MedSpa, is an intensive result-driven facial that bridges the gap between a light facial and a peel without having to wait for any downtime. It's designed to resurface the skin, improve rosacea symptoms, decrease acne scarring, diminish fine lines, and encourage cell renewal. It's an incredible treatment to give yourself a radiant glow.

Infections

The human body is made up of a complex set of organs and tissues which work together to guard against infection. Infections can be caused by microorganisms like parasites, viruses, and bacteria that infect healthy cells, causing them to multiply in uncontrolled ways. If this happens, your immune system may respond with symptoms of illness. These symptoms could range from a runny or stuffy nose to stomach upset, but they can also include a high fever, swollen glands, and a eruption. The type of infection and its location can affect your symptoms.

Infections can spread in a variety of ways however the most common are spread from person to through droplets that linger in the air after sneezing or coughing. Bacterial diseases such as tuberculosis and strep throat meningococcal diseases and Legionnaires' disease are spread in this manner, as do certain viral infections such as the common cold and influenza. Certain bacteria-related infections, like skin infections and sexually transmitted diseases (STIs) like gonorrhea and Chlamydia, can be transmitted through direct contact with infected tissues or ethanol biofuel fireplace fire (http://www.stes.tyc.edu.tw/xoops/modules/profile/userinfo.php?Uid=1829010) mucous membranes as well as indirect contact with contaminated surfaces. Certain bacterial infections are transmitted by insects like ticks, mosquitoes or fleas, and are spread when these bugs bite you.

Some parasites and viruses are small enough to enter your bloodstream and infect your cells, which can cause serious illness such as the common cold and AIDS. Fungi can cause a variety of skin ailments such as ringworm and athlete's foot. Some are a threat to the lungs and nervous system, such as the rabies virus.

The BioFire Panel utilizes our unique FilmArray Technology to test the bronchoalveolar and sputum samples for a comprehensive listing of pathogens involved in upper respiratory infections. The kit comes with a reagent bag that contains all the chemistry needed to perform reverse transcription, nested multiplex PCR and detection in one machine. It's a simple solution to aid clinicians in identifying and treat patients suffering from various respiratory symptoms. This test has been given an Emergency Use Authorization. It is available in bioMerieux CLIA medium and high complexity laboratories.